Is vancomycin redundant for serious staphylococcal infection?

Asthma is a Serious Danger

  میزان مرگ و میر آسم طی دهه گذشته بطور چشمگیری تغییر کرده است. با مبتلا کردن ۱۵ میلیون آمریکایی میزان مرگ و میر در سال ۱۹۷۸، به رقم ۱۸۷۲ نفر و ۹ سال بعد، به بیش از ۴۰۰۰ نفر رسید. علت چنین افزایش چشمگیری روشن نیست. علل احتمالی عبارتند از کاهش ظرفیت تنفس، استفاده بیش از حد از داروهای استثنائی و استنباط غلط بیماران و نیز مراکز درمانی نسبت به شدت بیماری است. بررسی دقیق، معالجات مناسب و آموزش به ب...

How much vancomycin dose is enough for the MRSA infection in pediatric patients with various degrees of renal function?

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

How much vancomycin dose is enough for the MRSA infection in pediatric patients with various degrees of renal function?

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

Serological tests for staphylococcal infection.

The need for a reliable serological test for occult staphylococcal infection has long been evident, especially for the diagnosis of lesions of the spine and hip. Earlier reports on the use of the anti-a-haemolysin (Lack and Shelswell, 1955; Lack, 1957), and anti-leucocidin tests (Towers and Gladstone, 1958; Towers, 1961) have placed us in a position to compare the value of these two tests; anti...

Staphylococcal infection in hospitals.